Education

• 2003 - 2008

  Department of Electrical Engineering, National Taiwan University, Taiwan

  Ph.D. in Electrical Engineering
• 2001 - 2003

  Department of Electrical Engineering, National Taiwan University, Taiwan

  M.S. in Electrical Engineering
• 1997 - 2001

  Department of Electrical Engineering, National Taiwan University, Taiwan

  B.S. in Electrical Engineering

Professional Experiences

• 2025/01 - present

  Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Taiwan

  Investigator
• 2023/08 - present

  Institute of Medical Device and Imaging, National Taiwan University College of Medicine, Taipei, Taiwan

  Adjunct Associate Professor
• 2023/08 - 2024/07

  Institute of Biomedical Engineering, National Yang Ming Chiao Tung University, Hsinchu, Taiwan

  Jointly Appointed Associate Professor
• 2019/07 - 2024/12

  Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Taiwan

  Associate Investigator
• 2013/07 - 2019/06

  Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Taiwan

  Assistant Investigator
• 2011/09 - 2013/06

  Division of Medical Engineering Research, National Health Research Institutes, Taiwan

  Assistant Investigator
• 2010/04 - 2011/08

  Advanced MRI Section, Laboratory of Functional and Molecular Imaging, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, USA

  Visiting Fellow
• 2009/06 - 2010/03

  Advanced Biomedical Lab, Center for Optoelectronic Biomedicine, National Taiwan University College of Medicine, Taipei, Taiwan

  Postdoctoral Research Fellow

Research Interests

• • MR physics and imaging methodology
  • Brain neuroimaging
  • Ultra-high-field MRI
  • MR system development

• • Biomedical signal and image processing
• • Medical imaging instrumentations

Research Activities

Editorial & Grant Review Services

• • 2023 – 2024, Grant Review Panel Member, Department of Life Sciences, NSTC (國科會生科處複審委員)
  • 2024 – Present, Associate Editor, Health and Technology
  • 2023 – Present, Editorial Board Member, Scientific Reports

Affiliations

• • 2024 – Present, Board Member (理事), Taiwan Magnetic Resonance Society
• • Member, Taiwanese Society of Biomedical Engineering (TSBME)
• • Member, International Society for Magnetic Resonance in Medicine (ISMRM)
• • Member, IEEE Engineering in Medicine and Biology Society (EMBS)

Honors & Awards

• • 2023 Gold Medal Award, 2023 Taiwan Innotech Expo Invention Contest, October 2023, Taipei, Taiwan
  • 2021 The ISMRM Summa Cum Laude Merit Award, ISMRM & SMRT Annual Meeting & Exhibition, May 2021
  • 2020 National Innovation Award, Taipei, Taiwan
  • 2020 2020 NHRI Research Achievement Award for Young Scientist, National Health Research Institutes, Miaoli County, Taiwan
  • 2014 National Invention and Creation Award, Taipei, Taiwan

International Conferences and Societies

• • Scientific Subcommittee Member, 2025 ISMRM Diffusion Workshop, Kyoto, Japan. (Feb 2025)
  • Session Moderator, The 10th International Conference on the Development of Biomedical Engineering in Vietnam, Phan Thiet City, Vietnam. (July 2024)
  • Session Moderator, The 2024 Taiwan Magnetic Resonance Society Annual Meeting, Taoyuan, Taiwan. (May 2024)
  • Session Moderator, The 2024 ISMRM & SMRT Annual Meeting, Singapore. (May 2024)
  • Session Moderator, The 2023 ISMRM & SMRT Annual Meeting, Toronto, Canada. (June 2023)
  • Session Moderator, The 4th ASMRM Annual Meeting, Taipei, Taiwan. (May 2022)
  • Session Moderator, The 6th International Symposium on Radiation Education, Taipei, Taiwan. (Aug. 2021)
  • Session Moderator, 2020 Annual TMRS Meeting on the Frontiers of Biological and Medicinal Magnetic Resonance, Taipei, Taiwan. (Dec. 2020)
  • Session Moderator, 5th International Workshop on MRI Phase Contrast & Quantitative Susceptibility Mapping, Seoul, Korea. (Sept. 2019)

Publications (2019-Present)

• 1. Sheng-Min Huang, Kuan-Hung Cho, Koping Chang, Pei-Hsin Huang*, Li-Wei Kuo*. Altered thalamocortical tract trajectory growth with undisrupted thalamic parcellation pattern in human lissencephaly brain at mid-gestational stage. Neurobiology of Disease, 2024;199:106577, September 2024, doi.org/10.1016/j.nbd.2024.106577.
  2. Sheng-Min Huang, Cheung-Ter Ong, Yu-Ching Huang*, Nan-Hao Chen, Ting-Kai Leung, Chun-Yinh Shen, Li-Wei Kuo*. Resting-state network analysis reveals altered functional brain connectivity in essential tremor. Brain Connectivity, 14 June 2024, doi.org/10.1089/brain.2024.0004.
  3. Jui-Hong Chien, I-Tzu Hung, Joshua Oon Soo Goh*, Li-Wei Kuo*, Wei-Wen Chang. Personal socio-cultural preferences modulate neural correlates of decisions to socialize with powerful persons. Human Brain Mapping, 2022;43:4422-4432, 1 October 2022, doi:10.1002/hbm.25963.
  4. Pei-Hsin Huang, Tseng-Yin Yang, Chia-Wei Yeh, Sheng-Min Huang, Ho-Ching Chang, Yun-Fen Hung, Wen-Chia Chu, Kuan-Hung Cho, Tzu-Pin Lu, Po-Hsiu Kuo, Li-Jen Lee, Li-Wei Kuo, Cheng-Chang Lien, Hwai-Jong Cheng. Involvement of a BH3-only apoptosis sensitizer gene Blm-s in hippocampus-mediated mood control. Translational Psychiatry, 12(1):411, 26 September 2022, doi:10.1038/s41398-022-02184-6.
  5. Yen-Hsuan Hsu, Sheng-Min Huang, Shih-Yen Lin, Jir-Jei Yang, Min-Chien Tu*, Li-Wei Kuo*. Prospective memory and default mode network functional connectivity in normal and pathological aging. Journal of Alzheimer’s Disease, 86(2):753-762, 22 March 2022, doi:10.3233/JAD-215293.
  6. Sabri Altunkaya^¥, Sheng-Min Huang^¥, Yen-Hsuan Hsu, Jir-Jei Yang, Chien-Yuan Lin, Li-Wei Kuo, Min-Chien Tu. Dissociable functional brain networks associated with apathy in subcortical ischemic vascular disease and Alzheimer’s disease. Frontiers in Aging Neuroscience, 13:717037, 3 February 2022, doi:10.3389/fnagi.2021.717037.
  7. Ezequiel Farrher*^¥, Chia-Wen Chiang^¥, Kuan-Hung Cho, Farida Grinberg, Richard P. Buschbeck, Ming-Jye Chen, Kuo-Jen Wu, Yun Wang, Sheng-Min Huang, Zaheer Abbas, Chang-Hoon Choi, N. Jon Shah, Li-Wei Kuo*. Spatiotemporal characterisation of ischaemic lesions in transient stroke animal models using diffusion free water elimination and mapping MRI with echo time dependence. NeuroImage, 244:118605, 1 December 2021, doi:10.1016/j.neuroimage.2021.118605.
  8. Min-Chien Tu, Sheng-Min Huang, Yen-Hsuan Hsu, Jir-Jei Yang, Chien-Yuan Lin, Li-Wei Kuo*. Discriminating Subcortical Ischemic Vascular Disease and Alzheimer’s Disease by Diffusion Kurtosis Imaging in Segregated Thalamic Regions. Human Brain Mapping, 42(7):2018-2031, May 2021, doi:10.1002/hbm.25342.
  9. Li-Wei Kuo^¥, Guo-Chung Dong¥, Chia-Ching Pan, Sheng-Fu Chen, Gin-Shin Chen. An MRI-guided ring high-intensity focused ultrasound system for noninvasive breast ablation. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control, 67(9):1839-1847, September 2020, doi:10.1109/TUFFC.2020.2992764. 
  10. Min-Chien Tu, Yen-Hsuan Hsu, Jir-Jei Yang, Wen-Hui Huang, Jie-Fu Deng, Shih-Yen Lin, Chien-Yuan Lin, Li-Wei Kuo*. Attention and functional connectivity among patients with early-stage subcortical ischemic vascular disease and Alzheimer’s disease. Frontiers in Aging Neuroscience, 12:239, August 2020, doi:10.3389/fnagi.2020.00239.
  11. Ezequiel Farrher*, Farida Grinberg, Li-Wei Kuo*, Kuan-Hung Cho, Richard P. Buschbeck, Ming-Jye Chen, Hsuan-Han Chiang, Chang-Hoon Choi, N. Jon Shah. Dedicated diffusion phantoms for the investigation of free water elimination and mapping: insights into the influence of T2 relaxation properties. NMR in Biomedicine, 33:e4210, April 2020, doi:10.1002/nbm.4210.
  12. Chia-Wen Chiang, Shih-Yen Lin, Kuan-Hung Cho, Kou-Jen Wu, Yun Wang, Li-Wei Kuo*. Effects of signal averaging, gradient encoding scheme, and spatial resolution on diffusion kurtosis imaging: An empirical study using 7T MRI. Journal of Magnetic Resonance Imaging, 50(5):1593-1603, November 2019, doi:10.1002/jmri.26755.
  13. Li-Wei Kuo*^¥, Pei-Sheng Lin^¥, Shih-Yen Lin, Ming-Fang Liu, Hengtai Jan, Hsin-Chien Lee, Sheng-Chang Wang*. Functional Correlates of Resting-state Connectivity in the Default Mode Network of Heroin Users on Methadone Treatment and Medication-free Therapeutic Community Program. Frontiers in Psychiatry, 10:381, June 2019, doi:10.3389/fpsyt.2019.00381.
  14. Kuan-Hung Cho, Sheng-Min Huang, Chang-Hoon Choi, Ming-Jye Chen, Hsuan-Han Chiang, Richard P. Buschbeck, Ezequiel Farrher, N. Jon Shah, Ruslan Garipov, Ching-Ping Chang, Hsu Chang, Li-Wei Kuo*. Development, integration and use of an ultra-high-strength gradient system on a human-size 3 T magnet for small animal MRI. PLoS One, 14(6):e0217916, June 2019, doi:10.1371/journal.pone.0217916.
  15. Shih-Yen Lin, Chi-Chun Lee, Yong-Sheng Chen, Li-Wei Kuo*. Investigation of functional brain network reconfiguration during vocal emotional processing using graph-theoretical analysis. Social Cognitive and Affective Neuroscience, 14(5):529-538, May 2019, doi:10.1093/scan/nsz025.
  16. Shih-Yen Lin, Chen-Pei Lin, Tsung-Jen Hsieh, Chung-Fen Lin, Sih-Huei Chen, Yi-Ping Chao, Yong-Sheng Chen, Chih-Cheng Hsu, Li-Wei Kuo*. Multiparametric Graph Theoretical Analysis Reveals Altered Structural and Functional Network Topology in Alzheimer’s Disease. Neuroimage: Clinical, 22:101680, January 2019, doi:10.1016/j.nicl.2019.101680.

• National Health Research Institutes - Institutional Repository: 6865

Patent

1. Li-Wei Kuo, Kuan-Hung Cho. 消除磁振造影中移動假影的方法. Taiwan Patent No. I792513, 11 February 2023.
2. Yi-Ping Chao, Li-Wei Kuo, Kuan-Hung Cho. 腦部磁振造影的頭動校正方法. Taiwan Patent No. I738523, 1 September 2021.
3. Fang-Ci Su, Hsin-Yi Tsai, Min-Wei Hung, Yi-Cheng Lin, Kuo-Cheng Huang, Hsin-Su Yu, Chiou-Lian Lai, Chung-Yao Hsu, Chao-Hung Cheng, Li-Wei Kuo. System and Method for Detecting Illuminance. Taiwan Patent No. I650535 B, 11 February 2019.
4. Yi-Cheng Lin, Hsin-Yi Tsai, Min-Wei Hung, Kuo-Cheng Huang, Hsin-Su Yu, Chiou-Lian Lai, Chung-Yao Hsu, Chao-Hung Cheng, Li-Wei Kuo, Hung-Che Chiang, Chih-Yi Yang. Composite Intelligent Biological Phototherapy Device. Taiwan Patent No. I645878 B, 1 January 2019.