陳景欣 博士

陳景欣 博士

副研究員

辦公室分機 37108

實驗室分機 37117

gschen@nhri.edu.tw

實驗室網站 

Education

  • 1998 - 2002
    National Cheng Kung University, Taiwan
    Ph.D. in Mechanical Engineering
  • 1996 - 1998
    National Cheng Kung University, Taiwan
    M.S. in Mechanical Engineering
  • 1993 - 1996
    National Chiao Tung University, Taiwan
    B.S. in Mechanical Engineering

Professional Experiences

  • 2014 - present
    Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Taiwan
    Associate Investigator
  • 2013 - 2014
    Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Taiwan
    Assistant Investigator
  • 2009 - 2013
    Division of Medical Engineering Research, National Health Research Institutes, Taiwan
    Assistant Investigator
  • 2007 - 2008
    NIH Ultrasound Transducer Resources Center, University of Southern California, USA
    Visiting Scholar
  • 2006 - 2009
    Division of Medical Engineering Research, National Health Research Institutes, Taiwan
    Research Associate
  • 2006
    Department of Automatic Control Engineering, Feng Chia University, Taiwan
    Adjunct Assistant Professor
  • 2002 - 2006
    Division of Medical Engineering Research, National Health Research Institutes, Taiwan
    Postdoctoral Fellow

Research Interests

Dr. Chen’s research interests include the development of ultrasound transducers dedicated for various biomedical applications; advancement of high-intensity focused ultrasound (HIFU) transducer technology; therapy of solid tumors by HIFU ablation; effects of ultrasound on peripheral neuropathic nerves.

Research Activities & Accomplishment

The strategy of Dr. Chen’s laboratory is to use the ultrasonic technology to create novel treatment modalities and devices for clinical diseases. The ultimate goal is to provide surgeons or clinicians a new tool to treat diseases which can’t be treated with current operations or to improve the efficacy of the treatment or to lower the surgical risk.Dr. Chen has established the ultrasonic transducer technology in Taiwan. Based on the technology platform, three kinds of array HIFU transducers such as cylindrical, dual-curvature and annular transducers for tumor ablation and an A-mode transducer for guidance of needle insertion have been developed and validated by in vitro or/and in vivo animal studies. Furthermore, the optimal design of piezocomposites for HIFU transducer applications has been investigated. A design guideline for HIFU transducer engineers has been built. On the other hand, He has conducted the feasibility study of nerve conduction blockade by HIFU for pain relief. In vitro and in vivo animal studies demonstrated that the reversible conduction blockage of normal and diabetic neuropathic rat sciatic nerves can be achieved using HIFU treatment.

  • Member, Taiwanese Society of Biomedical Engineering
  • Member, International Society for Therapeutic Ultrasound
  • Member, IEEE Society
  • Reviewer, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
  • Reviewer, Journal of Medical and Biological Engineering
  • Reviewer, PLOS ONE
  • Reviewer, IEEE Transactions on Biomedical Engineering

Selected Publications

  1. Lee YF, Lin CC, Cheng JS, Chen GS*. Nerve conduction blockage of diabetic rats by high-intensity focused ultrasound for analgesia applications. British Journal of Anaesthesia 2015; DOI: 10.1093/bja/aeu443.

  2. Lee YF, Lin CC, Cheng JS, Chen GS*. High-intensity focused ultrasound attenuates neural responses of sciatic nerves isolated from normal or neuropathic rats. Ultrasound in Medicine and Biology 2015; 41:132-142.

  3. Lee YF, Lin CC*, Chen GS*. Temporal course of streptozotocin-induced diabetic polyneuropathy in rats. Neurological Sciences 2014; 35:1813-1820.

  4. Shieh J, Chen SR, Chen GS, Lo CW, Chen CS, Chen BT, Sun MK, Huang CW, Chen WS*. Acrylic acid controlled reusable temperature-sensitive hydrogel phantoms for thermal ablation therapy. Applied Thermal Engineering 2014; 62:322-329.

  5. Huang SY, Ko CE, Chen GS, Chung IF, Yang FY*. Focused ultrasound simultaneous irradiation/MRI imaging, and two-stage general kinetic model. PLOS ONE 2014; 9(6): e100280.

  6. Chen GS*, Chang YC, Chang Y, Cheng JS. A prototype axial ultrasound needle guide to reduce epidural bone contact. Anaesthesia 2014; 69:746-751.

  7. Chen GS*, Lee YF, Cheng JS. Measurement of ultrasonic attenuation in diabetic neuropathic sciatic nerves for diagnostic and therapeutic applications. Annals of Biomedical Engineering 2014; 42:1749-1759.

  8. Chen GS*, Pan CC, Lin YL, Cheng JS. Assessing the relationship between the inter-rod coupling and the efficiency of piezocomposite high-intensity focused ultrasound transducers. Ultrasonics 2014; 54:789-794.

  9. Chen GS*, Liu HC, Lin YC, Lin YL. Experimental analysis of 1-3 piezocomposites for high-intensity focused ultrasound transducer applications. IEEE Transactions on Biomedical Engineering 2013; 60:128-134.

  10. Chen GS*, Lin CY, Jeong JS, Cannata JM, Lin WL, Chang H, Shung KK. Design and characterization of dual-curvature 1.5-dimensional high-intensity focused ultrasound phased-array transducer. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 2012; 59:150-155.

National Health Research Institutes - Institutional Repository: 3807

Patent

專利名稱
專利號碼
專利發明人
A contact-type piezoresistive micro-shear stress sensor 144224 Fang YK, Ju MS, Ho JJ, Chen GS, Hsieh MC, Ting SF, Wu CS
Dual-curvature phased array high-intensity focused ultrasound transducer for tumor therapy 8,888,706 Chen GS, Chang H, Lin WL
一種偵測拉普拉斯腦電波訊號之感測元件及其偵測方法 (Sensor Device for Detecting LEEG Signals and Detecting Method Thereof) I317629 盧智成、陳景欣、陳聖夫、朱銘祥、林宙晴
非侵入式破壞脂肪組織與促進脂質代謝之方法與元件 I507228 陳景欣、林宙晴