1998 - 2002National Cheng Kung University, TaiwanPh.D. in Mechanical Engineering
1996 - 1998National Cheng Kung University, TaiwanM.S. in Mechanical Engineering
1993 - 1996National Chiao Tung University, TaiwanB.S. in Mechanical Engineering
2014 - presentInstitute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, TaiwanAssociate Investigator
2013 - 2014Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, TaiwanAssistant Investigator
2009 - 2013Division of Medical Engineering Research, National Health Research Institutes, TaiwanAssistant Investigator
2007 - 2008NIH Ultrasound Transducer Resources Center, University of Southern California, USAVisiting Scholar
2006 - 2009Division of Medical Engineering Research, National Health Research Institutes, TaiwanResearch Associate
2006Department of Automatic Control Engineering, Feng Chia University, TaiwanAdjunct Assistant Professor
2002 - 2006Division of Medical Engineering Research, National Health Research Institutes, TaiwanPostdoctoral Fellow
Dr. Chen’s research interests include the development of ultrasound transducers dedicated for various biomedical applications; advancement of high-intensity focused ultrasound (HIFU) transducer technology; therapy of solid tumors by HIFU ablation; effects of ultrasound on peripheral neuropathic nerves.
Research Activities & Accomplishment
The strategy of Dr. Chen’s laboratory is to use the ultrasonic technology to create novel treatment modalities and devices for clinical diseases. The ultimate goal is to provide surgeons or clinicians a new tool to treat diseases which can’t be treated with current operations or to improve the efficacy of the treatment or to lower the surgical risk.Dr. Chen has established the ultrasonic transducer technology in Taiwan. Based on the technology platform, three kinds of array HIFU transducers such as cylindrical, dual-curvature and annular transducers for tumor ablation and an A-mode transducer for guidance of needle insertion have been developed and validated by in vitro or/and in vivo animal studies. Furthermore, the optimal design of piezocomposites for HIFU transducer applications has been investigated. A design guideline for HIFU transducer engineers has been built. On the other hand, He has conducted the feasibility study of nerve conduction blockade by HIFU for pain relief. In vitro and in vivo animal studies demonstrated that the reversible conduction blockage of normal and diabetic neuropathic rat sciatic nerves can be achieved using HIFU treatment.
- Member, Taiwanese Society of Biomedical Engineering
- Member, International Society for Therapeutic Ultrasound
- Member, IEEE Society
- Reviewer, IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
- Reviewer, Journal of Medical and Biological Engineering
- Reviewer, PLOS ONE
- Reviewer, IEEE Transactions on Biomedical Engineering
Lee YF, Lin CC, Cheng JS, Chen GS*. Nerve conduction blockage of diabetic rats by high-intensity focused ultrasound for analgesia applications. British Journal of Anaesthesia 2015; DOI: 10.1093/bja/aeu443.
Lee YF, Lin CC, Cheng JS, Chen GS*. High-intensity focused ultrasound attenuates neural responses of sciatic nerves isolated from normal or neuropathic rats. Ultrasound in Medicine and Biology 2015; 41:132-142.
Lee YF, Lin CC*, Chen GS*. Temporal course of streptozotocin-induced diabetic polyneuropathy in rats. Neurological Sciences 2014; 35:1813-1820.
Shieh J, Chen SR, Chen GS, Lo CW, Chen CS, Chen BT, Sun MK, Huang CW, Chen WS*. Acrylic acid controlled reusable temperature-sensitive hydrogel phantoms for thermal ablation therapy. Applied Thermal Engineering 2014; 62:322-329.
Huang SY, Ko CE, Chen GS, Chung IF, Yang FY*. Focused ultrasound simultaneous irradiation/MRI imaging, and two-stage general kinetic model. PLOS ONE 2014; 9(6): e100280.
Chen GS*, Chang YC, Chang Y, Cheng JS. A prototype axial ultrasound needle guide to reduce epidural bone contact. Anaesthesia 2014; 69:746-751.
Chen GS*, Lee YF, Cheng JS. Measurement of ultrasonic attenuation in diabetic neuropathic sciatic nerves for diagnostic and therapeutic applications. Annals of Biomedical Engineering 2014; 42:1749-1759.
Chen GS*, Pan CC, Lin YL, Cheng JS. Assessing the relationship between the inter-rod coupling and the efficiency of piezocomposite high-intensity focused ultrasound transducers. Ultrasonics 2014; 54:789-794.
Chen GS*, Liu HC, Lin YC, Lin YL. Experimental analysis of 1-3 piezocomposites for high-intensity focused ultrasound transducer applications. IEEE Transactions on Biomedical Engineering 2013; 60:128-134.
Chen GS*, Lin CY, Jeong JS, Cannata JM, Lin WL, Chang H, Shung KK. Design and characterization of dual-curvature 1.5-dimensional high-intensity focused ultrasound phased-array transducer. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 2012; 59:150-155.
National Health Research Institutes - Institutional Repository: 3807
|A contact-type piezoresistive micro-shear stress sensor||144224||Fang YK, Ju MS, Ho JJ, Chen GS, Hsieh MC, Ting SF, Wu CS|
|Dual-curvature phased array high-intensity focused ultrasound transducer for tumor therapy||8,888,706||Chen GS, Chang H, Lin WL|
|一種偵測拉普拉斯腦電波訊號之感測元件及其偵測方法 (Sensor Device for Detecting LEEG Signals and Detecting Method Thereof)||I317629||盧智成、陳景欣、陳聖夫、朱銘祥、林宙晴|