陳仁焜 博士

陳仁焜 博士

副研究員

辦公室分機 38117

實驗室分機 38119

jkchen@nhri.edu.tw

實驗室網站 

Education

  • 2000 - 2004
    Department of Chemistry, National Tsing Hua University
    Ph.D. in Chemistry
  • 1996 - 1998
    Department of Nuclear Science, National Tsing Hua University
    M.S. in Nuclear Science
  • 1992 - 1996
    Department of Chemistry, National Tsing Hua University
    B.S. in Chemistry

Professional Experiences

  • 2013.07 - present
    Institute of Biomedical Engineering and Nanomedicine, National Health Research Institutes, Taiwan
    Assistant Investigator
  • 2011.04 - 2013.07
    Center for Nanomedicine Research, NHRI, Taiwan
    Assistant Investigator
  • 2011 - present
    School of Dentistry, National Defense Medical Center, Taipei, Taiwan
    Adjunct Assistant Professor
  • 2007.04 - 2011.03
    Center for Nanomedicine Research, NHRI, Taiwan
    Postdoctoral Research Fellow
  • 2005.05 - 2007.04
    Clinical Proteomics Center, Chang Gung Memorial Hospital, Taoyuan, Taiwan
    Research Associate
  • 2004.09 - 2005.04
    Core Facility for Proteomics Research, Institute of Biochemistry, Academia Sinica, Taipei, Taiwan
    Postdoctoral Research Fellow
  • 1997.07 - 2000.09
    Product Process and Chemistry Division, Food Industrial Research and Development Institute (FIRDI), Taiwan
    Associate Research Scientist

Research Interests

  • Inhalation Medicine
  • Radiopharmaceuticals for Imaging & Therapy
  • NanoSafety
  • BioAnalytical Chemistry: chromatography, mass spectrometry and imaging technology

Research Activities & Accomplishment

  • 2013: The 10th National Innovation Award, “Treating Brain Tumor with Gold Nanoparticle Fusion Therapy”
  • 2013: Supervisor of master student Ting-Yu Cheng (NTHU), won the “Outstanding Poster Award in the International Symposium of Chemical-Environmental-Biomedical Technology 2013 (Tohoku University, Sendai, Japan)”
  • 2004: Outstanding award of dissertation in analytical/physical chemistry, Chinese Chemical Society, Taiwan 1998: The Archilife research scholarship of master thesis in public health division, Archilife Research Foundation 1996: Outstanding research award for under-graduated student, National Science Council, Taiwan
  • 1994: Outstanding student award, National Tsing Hua University
  • 1994, 1995 & 1996: Scholarship for undergraduate student, National Tsing Hua University.

Selected Publications

  1. Chen, J.K., Ho, C.C., Chang, H., Lin, J.F., Yang, C.S., Tsai, M.H., Tsai, H.T. & Lin, P. Particulate nature of inhaled zinc oxide nanoparticles determines systemic effects and mechanisms of pulmonary inflammation in mice. Nanotoxicology 9, 43-53 (2015). (5-Year IF: 7.766, Journal ranking: 2/87 in TOXICOLOGY, Quartile in Category: Q1)(Journal ranking: 10/73 in NANOSCIENCE & NANOTECHNOLOGY, Quartile in Category: Q1)

  2. Chen, C.H., Lin, F.S., Liao, W.N., Liang, S.L., Chen, M.H., Chen, Y.W., Lin, W.Y., Hsu, M.H., Wang, M.Y., Peir, J.J., Chou, F.I., Chen, C.Y., Chen, S.Y., Huang, S.C., Yang, M.H., Hueng, D.Y., Hwu, Y., Yang, C.S. & Chen, J.K. Establishment of a trimodality analytical platform for tracing, imaging and quantification of gold nanoparticles in animals by radiotracer techniques. Anal. Chem. 87, 601-608 (2015). (5-Year IF: 5.966, Journal ranking: 4/76 in CHEMISTRY, ANALYTICAL, Quartile in Category: Q1) MOST 101-2113-M-400-001-MY2.

  3. Huang, Y.C., Chen, J.K., Lam, U.I. & Chen, S.Y. Preparing, characterizing, and evaluating chitosan/fucoidan nanoparticles as oral delivery carriers. Journal of Polymer Research 21, 415 (2014). (IF: 1.897, Journal ranking: 34/82 in POLYMER SCIENCE, Quartile in Category: Q2) MOST 101-2113-M-400-001-MY2.

  4. Sherlock Huang, L.C., Hsieh, W.Y., Chen, J.Y., Huang, S.C., Chen, J.K. & Hsu, M.H. Drug delivery system design and development for boron neutron capture therapy on cancer treatment. Appl. Radiat. Isot. 88, 89-93 (2014). (IF: 1.056, Journal ranking: 15/33 in NUCLEAR SCIENCE & TECHNOLOGY, Quartile in Category: Q2) MOST 101-2113-M-400-001-MY2.

  5. Hsu, M.H., Chuang, H., Cheng, F.Y., Huang, Y.P., Han, C.C., Chen, J.Y., Huang, S.C., Chen, J.K., Wu, D.S., Chu, H.L. & Chang, C.C. Directly thiolated modification onto the surface of detonation nanodiamonds. ACS Applied Materials & Interfaces 6, 7198-7203 (2014). (IF: 5.900, Journal ranking: 26/251 in MATERIALS SCIENCE, MULTIDISCIPLINARY, Quartile in Category: Q1) (Journal ranking: 16/73 in NANOSCIENCE & NANOTECHNOLOGY, Quartile in Category: Q1) MOST 101-2113-M-400-001-MY2.

  6. Liu, C.P., Lin, F.S., Chien, C.T., Tseng, S.Y., Luo, C.W., Chen, C.H., Chen, J.K., Tseng, F.G., Hwu, Y., Lo, L.W., Yang, C.S. & Lin, S.Y. In-situ Formation and Assembly of Gold Nanoparticles by Gum Arabic as Efficient Photothermal Agent for Killing Cancer Cells. Macromol. Biosci.(2013)

  7. Tai, L.A., Kang, Y.T., Chen, Y.C., Wang, Y.C., Wang, Y.J., Wu, Y.T., Liu, K.L., Wang, C.Y., Ko, Y.F., Chen, C.Y., Huang, N.C., Chen, J.K., Hsieh, Y.F., Yew, T.R. & Yang, C.S. Quantitative characterization of nanoparticles in blood by transmission electron microscopy with a window-type microchip nanopipet. Anal. Chem. 84, 6312-6316 (2012).

  8. Yeh, T.K., Chen, J.K., Lin, C.H., Yang, M.H., Yang, C.S., Chou, F.I., Peir, J.J., Wang, M.Y., Chang, W.H., Tsai, M.H., Tsai, H.T. & Lin, P. Kinetics and tissue distribution of neutron-activated zinc oxide nanoparticles and zinc nitrate in mice: effects of size and particulate nature. Nanotechnology 23, 085102 (2012). (5-Year IF: 3.867, Journal ranking: 39/251 in MATERIALS SCIENCE, MULTIDISCIPLINARY, Quartile in Category: Q1)

  9. Chen, J.K., Zhan, Y.J., Yang, C.S. & Tzeng, S.F. Oxidative stress-induced attenuation of thrombospondin-1 expression in primary rat astrocytes.J. Cell. Biochem. 112, 59-70 (2011)

  10. Chen, J.K., Shih, M.H., Peir, J.J., Liu, C.H., Chou, F.I., Lai, W.H., Chang, L.W., Lin, P., Wang, M.Y., Yang, M.H. & Yang, C.S. The use of radioactive zinc oxide nanoparticles in determination of their tissue concentrations following intravenous administration in mice. Analyst 135, 1742-1746 (2010).

National Health Research Institutes - Institutional Repository: 5483

Patent

專利名稱 專利國 專利號 發明人
固相金奈米顆粒之合成 ROC I 445664 李佳洪、廖威能 程士勳、陳仁焜 楊重熙、羅履維、胡宇光
SOLID PHASE GOLD NANOPARTICLE SYNTHESIS US US 8,734,844 李佳洪、廖威能 程士勳、陳仁焜 楊重熙、羅履維、胡宇光