In Vivo Mapping of The Human Brain Connectome
時間地點：10:30 am, Sep 29 (Thu), 2022; R1-B1122 Conference Room
研討講者：Ching-Po Lin, Ph.D.
September 16, 2022
Ching-Po Lin, Ph.D.
Institute of Neuroscience
National Yang Ming Chiao Tung University
Ching-Po Lin, Ph.D.
Distinguished Professor,
Institute of Neuroscience,
National Yang Ming Chiao Tung University, Taipei, Taiwan
EDUCATIONS
09/1996 - 01/2002 PhD, Division of Biomedical Engineering, Department of Electrical Engineering,National Taiwan University, Taiwan
09/1991 - 07/1993 MS, Institute of Biomedical Engineering, National Yang-Ming University, Taiwan
09/1987 - 07/1991 BS, Department of Physics, National Central University, Taiwan PROFESSIONAL
EXPERIENCES
02/2018 - present Distinguished Professor, Institute of Neuroscience, National Yang Ming Chiao Tung University, Taiwan
02/2012 - present Professor (with Tenure), Institute of Neuroscience, National Yang-Ming University, Taiwan
02/2009 - 01/2012 Associate Professor (with Tenure), Institute of Neuroscience, National Yang Ming University, Taiwan
02/2004 - 01/2009 Assistant Professor, Institute of Neuroscience, National Yang-Ming University, Taiwan
02/2002 - 01/2004 Postdoctoral Fellow, Institute of Electrical Engineering, National Taiwan University, Taiwan
09/1995 - 06/1996 Network Engineer, Institute for Information Industry, Taiwan
09/1993 - 08/1995 Department Staff, National Health Research Institute, Taiwan
ADMINISTRATIVE EXPERIENCES
08/2022 - present Associate Dean of General Affairs, National Yang Ming Chiao Tung University, Taiwan
02/2022 - present Deputy Director, Medical Device Innovation and Translation R&D Center, National Yang Ming Chiao Tung University, Taiwan
02/2016 - 01/2022 Deputy Director, Aging and Health Research Center, National Yang Ming Chiao Tung University, Taiwan
10/2008 - present Director, MRI Core Facility, National Yang Ming Chiao Tung University, Taiwan
AWARDS AND HONOR
2021 Future Tech Award, Ministry of Science and Technology, Taiwan
2020 National Innovation Award, Taiwan
2020 Professor with permanently exempt from assessment, National Yang Ming Chiao Tung University
2019 PAC Model Award, Predictive Analytics Competition
2016 Award for executing Innovative Research Grant 3 times, National Health Research Institute
2016 12th The G. Nappi Cluster Headache Award
2011 12th The G. Nappi Cluster Headache Award
JOURNAL EDITORIAL ACTIVITIES
1. Associate Editor: Brain Connectivity
2. Associate Editor: Frontiers in Neuroscience, Section in Brain Imaging Methods
3. Editorial Board: Plos One
GRANT REVIEWING ACTIVITIES
1. Medical Research Council (MRC), UK (2017)
2. Agence Nationale De La Recherche (ANR), France (2013, 2014)
3. Ministry of Science and Technology, Taiwan (2000 – present)
ACADEMIC SOCIETY ACTIVITIES
1. Committee member, Asian Society of Magnetic Resonance in Medicine (2021 - present)
2. Committee member, Taiwan Magnetic Resonance Society (2020 - present)
3. Program committee: Organization for Human Brain Mapping (2010, 2011)
GRANTS DURING THE PAST FIVE YEARS
1. Development of micro brain surgery navigation system: Fusion of AI face recognition and brain image features for accurate positioning. MOST Emerging Technology Application Program (PI; 2022/1/1-2023/12/31; NTD 3,260,000)
2. Mapping the human brain connectome: Bridging microscale and macroscale organization. MOST Brain Project (PI; 2021/1/1-2022/12/31; NTD 18,000,000)
3. Mapping the human connectome: Bridging microscale and macroscale connectomics of the human brain. MOST Pre-Brain Project (PI; 2019/6/1-2020/12/31; NTD 9,500,000)
4. Cognitive Aging and Enhancement: Neural Basis of Scaffolding Theory of Aging and Cognition. MOST Brain and Cognitive Sciences Project (PI; 2018/1/1-2020/6/30; NTD 5,000,000)
5. Constructing Healthy Living in Super-Aged Society by Artificial Intelligence: From Geroprotective Intervention to Care Management. MOST (Co-PI; 2018/1/1-2021/12/31; NTD 60,000,000)
6. Brain network changes in first-episode schizophrenia progression: extension of imaging endophenotype. NHRI (PI; 2017/1/1-2019/12/31; NTD 7,500,000)
PATENTS
1. Patent Number: I 504382 (Taiwan) Title: A dental stimulator brain imaging Inventors: CP Lin, CP Jao Valid: 2015 - 2035
2. Patent Number: I614627 (Taiwan) Title: A method for neural tracts tracking (It has been technology transferred) Inventors: CP Lin, CY Lo, CT Chong Valid: 2018 - 2037
3. Patent Number: I679652 (Taiwan) Title: Method for individual brain morphometry assess Inventors: CP Lin, WC Lin, KH Chou Valid: 2019 - 2039
4. Patent Number: 10,497,120B2 (USA) Title: Method and apparatus of fiber tracing, and non-transitory computer-readable medium Inventors: CP Lin, CY Lo, CT Chong, CC Huang (It has been technology transferred) Valid: 2019 - 2040
5. Patent Number: I726574B (Taiwan) Title: Method for model training and electric device Inventors: CP Lin , LK Chen, KH Chou, CD Hsieh, CS Yu, SY Huang, MC Cheng Valid: 2020 - 2040
6. Patent Number: approved, waiting for license (Taiwan) Title: Method for White matter-based neurovascular age prediction Inventors: CP Lin, CC Huang Valid: 2022- 2042
INVITED TALKS DURING THE PAST SIX YEARS
1. Multimodal Integration- Combining DTI and fcMRI, 7th Biennial Conference on Resting State Brain Connectivity, Dallas, Texas, USA (Sep, 2019)
2. Mapping the connectomics of human brain disorders, ISMRM, Montreal, Canada (May, 2019)
3. Artificial intelligence in aging brain science, Shanghai innovation forum, Shanghai, China (Jul, 2018)
4. Mapping the structural connections in the living human brain, IEEE EMBS Neural Engineering Summer School, Shanghai, China (Aug. 2017)
5. Mapping the connectomics of human brain disorders, IEEE EMBS Neural Engineering Summer School, Shanghai, China (Aug. 2017)
6. Diffusion MRI Tractography for Neurosurgery, WFNS 16th World Congress of Neurosurgery, Istanbul, Turkey (Aug. 2017)
7. Reorganization of Brain Connectivity during Sleep, 1st Scientific and clinical meeting for sleep medicine, Suzhou, China (Nov. 2016)
8. Multimodal Integration- Combining DTI and fcMRI, 5th Biennial Conference on Resting State Brain Connectivity, Vienna, Austria (Sep. 2016)
PUBLICATIONS (僅列出今年度)
Total Number of Citations = 13863; H-Factor = 51
1. 1. Chu-Chung Huang, Kun-Hsien Chou, Wei-Ju Lee, Albert C. Yang, Shih-Jen Tsai, Liang-Kung Chen, Chih-Ping Chung*, Ching-Po Lin*. Brain white matter hyperintensities-predicted age reflects neurovascular health in middle-to-old aged subjects. Age & Ageing 2022 51(5):afac106
2. Yi-Chia Kung, Chia-Wei Li, Fan-Chi Hsiao, Pei-Jung Tsai, Shuo Chen, Ming-Kang Li, Hsin-Chien Lee, Chun-Yen Chang, Changwei W. Wu, Ching-Po Lin*. Cross-scale Dynamicity of Entropy and Connectivity in the Sleeping Brain. Brain Connectivity 2022 (in press)
3. Chih-Chin Heather Hsu, Shin Tai Chong, Yi-Chia Kung, Kuan-Tsen Kuo, Chu-Chung Huang, Ching-Po Lin*. Integrated Diffusion Image Operator (iDIO): A tool for automated configuration and processing of diffusion MRI data. bioRxiv 2022. https://doi.org/10.1101/2022.03.14.483870
4. Yi-Chia Wei, Yi-Chia Kung, Wen-Yi Huang, Chemin Lin, Yao-Liang Chen, Chih-Ken Chen, Yu-Chiau Shyu, Ching-Po Lin*. Functional Connectivity Dynamics Altered of the Resting Brain in Subjective Cognitive Decline. Frontiers in Aging Neuroscience, section Neurocognitive Aging and Behavior 2022 (In press)
5. Yi-Chia Wei, Wen-Yi Huang, Chih-Yu Jian, Chih-Chin Heather Hsu, Chih-Chung Hsu, Ching-Po Lin, Chi-Tung Cheng, Yao-Liang Chen, Hung-Yu Wei, Kuan-Fu Chen. Semantic segmentation guided detector for segmentation, classification, and lesion mapping of acute ischemic stroke in MRI images. NeuroImage: Clinical 2022; 103044
6. Chih-Ping Chung, Li-Ning Peng, Wei-Ju Lee, Pei-Ning Wang, Ching-Po Lin, Liang-Kung Chen. Cerebral small vessel disease is associated with concurrent physical and cognitive impairments at preclinical stage. Cerebral Circulation - Cognition and Behavior 2022; 3: 100144
7. Mingrui Xia, Jin Liu, Andrea Mechelli, Xiaoyi Sun, Qing Ma, Xiaoqin Wang, Dongtao Wei, Yuan Chen, Bangshan Liu, Chu-Chung Huang, Yanting Zheng, Yankun Wu, Taolin Chen, Yuqi Cheng, Xiufeng Xu, Qiyong Gong, Tian-Mei Si, Shijun Qiu, Ching-Po Lin, Jingliang Cheng, Yanqing Tang, Fei Wang, Jiang Qiu, Peng Xie, Lingjiang Li, Yong He. Connectome Gradient Dysfunction in Major Depression and Its Association with Gene Expression Profiles and Treatment Outcomes. Molecular Psychiatry 27(3): 1384-1393 (2022)
8. Chia-Shu Lin, Li-Kuo Liu, Wei-Ju Lee, Li-Ning Peng, Ching-Po Lin, Shyh-Yuan Lee, Liang-Kung Chen. Low masseter muscle mass is associated with frailty in community-dwelling older adults: I-Lan Longitudinal Aging Study. Experimental Gerontology 2022; 163:111777
9. Kai Niu, Xueyan Li, Li Zhang, Zhensong Yan, Wei Yu, Peipeng Liang, Yan Wang, Ching-Po Lin, Huimao Zhang, Chunjie Guo, Kuncheng Li, Tianyi Qian. Improving segmentation reliability of multi-scanner brain images using a generative adversarial network. Quant Imaging Med Surg. 2022; 12(3):1775-1786
10. Yi-Cheng Lin, Yun R Lien, Shang-Hua N. Lin, Yi-Chia Kung, Chu-Chung Huang, Ching-Po Lin, Li-Hung Chang Baseline cerebro-cerebellar functional connectivity in afferent and efferent pathways reveal dissociable improvements in visuomotor learning. Frontiers in Neuroscience 2022; 16: 904564
11. Yun Lien, Yi-Cheng Lin, Shang-Hua N. Lin, Ching-Po Lin, Li-Hung Chang. Frequency-dependent effects of cerebellar rTMS on visuomotor accuracy. Frontiers in Neuroscience 2022; 16: 804027
12. Chu-Chung Huang, Edmund T. Rolls, Jianfeng Feng, Ching-Po Lin. An extended Human Connectome Project multimodal parcellation atlas of the human cortex and subcortical areas. Brain Structure and Function 227(3): 763-778 (2022)
13. I-Ting Lee, Chu-Chung Huang, Po-Cheng Hsu, Ching-Po Lin, Po-Yi Tsai. Resting-State Network Changes Following Transcranial Magnetic Stimulation in Patients with Aphasia-A Randomized Controlled Study. Neuromodulation: Technology at the Neural Interface 2022 25(4):528-537
14. Po-Yuan Su, Yi-Chia Wei, Hao Luo, Chi-Hung Liu, Wen-Yi Huang, Kuan-Fu Chen, Ching-Po Lin, Hung-Yu Wei, Tsong-Hai Lee. Machine Learning Models for Predicting Influential Factors of Early Outcomes in Acute Ischemic Stroke: Registry-Based Study. JMIR Med Inform 2022;10(3):e32508
15. Cheng-Chia Lee, Sheng-Che Hung, Yi-Hsiu Chen, Hsin-Hung Chen, Chien Chen, Ching-Jen Chen, Hsiu-Mei Wu, Ching-Po Lin, Syu-Jyun Peng. Structural connectivity in children after total corpus callosotomy. Epilepsy Research 2022; 182: 106908
16. Tony Szu-Hsien Lee, Yi-Hsuan Liu, Yun-Ju Huang, Wai-Kwong Tang, Yifan Wang, Sien Hu, Ching-Po Lin, Chiang-Shan Ray Li, Chia-Chun Hung. Clinical and behavior characteristics of individuals who used ketamine. Scientific Reports 2022; 12(1):801
17. Hung Yu Liu, Kun-Hsien Chou, Pei-Lin Lee, Yen-Feng Wang, Shih-Pin Chen, Kuan-Lin Lai, Ching-Po Lin, Shuu-Jiun Wang, Wei-Ta Chen. The right anterior insula is associated with pain generalization in patients with fibromyalgia. Pain 2022; 163(4):e572-e579
18. Qiuyun Fan, Cornelius Eichner, Maryam Afzali, Lars Mueller, Chantal M.W. Tax, Mathias Davids, Mirsad Mahmutovic, Boris Keil, Berkin Bilgic, Kawin Setsompop, Hong-Hsi Lee, Qiyuan Tian, Chiara Maffei, Gabriel Ramos-Llordén, Aapo Nummenmaa, Thomas Witzel, Anastasia Yendiki, Yi-Qiao Song, Chu-Chung Huang, Ching-Po Lin, Nikolaus Weiskopf, Alfred Anwander, Derek K. Jones, Bruce R. Rosen, Lawrence L. Wald, Susie Y. Huang. Mapping the Human Connectome using Diffusion MRI at 300 mT/m Gradient Strength: Methodological Advances and Scientific Impact. Neuroimage 22;118958 (2022)
19. Wei Zhao, Valerie Voon, Kangkang Xue, Chao Xie, Jujiao Kang, Ching-Po Lin, Jijun Wang, Jingliang Cheng, Jianfeng Feng. Common abnormal connectivity in first-episode and chronic schizophrenia in pre- and post-central regions: Implications for neuromodulation targeting. Prog Neuropsychopharmacol Biol Psychiatry 117: 110556 (2022)
20. Chih-Ping Chung, Wei-Ju Lee, Kun-Hsien Chou, Pei-Lin Lee, Li-Ning Peng, Pei-Ning Wang, Ching-Po Lin, Liang-Kung Chen. Frailty and dementia risks in asymptomatic cerebral small vessel disease: A longitudinal cohort study. Archives of Gerontology and Geriatrics. 102: 104754 (2022)
21. Yi-Cheng Lin, Chih-Ping Chung, Pei-Lin Lee, Kun-Hsien Chou, Li-Hung Chang, Szu-Ying Lin, Yi-Jung Lee, Ching-Po Lin, Pei-Ning Wang. The Flexibility of Physio-Cognitive Decline Syndrome: A Longitudinal Cohort Study. Front Public Health. 10: 820383 (2022)
22. Yu Zhou, Xiaopeng Si, Yuanyuan Chen, Yiping Chao, Ching-Po Lin, Sicheng Li, Xingjian Zhang, Dong Ming , Qiang Li. Hippocampus- and Thalamus-Related Fiber-Specific White Matter Reductions in Mild Cognitive Impairment. Cerebral Cortex 2022; (in press)
23. Yajuan Zhang, Qiong Xiang, Chu-Chung Huang, Jiajia Zhao, Yuchen Liu, Ching-Po Lin, Dengtang Liu*, Chun Yi Zac Lo*. Short-term Medication Effects on Brain Functional Activity and Network Architecture in First-Episode Psychosis: A Longitudinal fMRI Study. Brain Imaging Behav. (in press
Ching-Po Lin, Ph.D.
Institute of Neuroscience
National Yang Ming Chiao Tung University
Ching-Po Lin, Ph.D.
Distinguished Professor,
Institute of Neuroscience,
National Yang Ming Chiao Tung University, Taipei, Taiwan
EDUCATIONS
09/1996 - 01/2002 PhD, Division of Biomedical Engineering, Department of Electrical Engineering,National Taiwan University, Taiwan
09/1991 - 07/1993 MS, Institute of Biomedical Engineering, National Yang-Ming University, Taiwan
09/1987 - 07/1991 BS, Department of Physics, National Central University, Taiwan PROFESSIONAL
EXPERIENCES
02/2018 - present Distinguished Professor, Institute of Neuroscience, National Yang Ming Chiao Tung University, Taiwan
02/2012 - present Professor (with Tenure), Institute of Neuroscience, National Yang-Ming University, Taiwan
02/2009 - 01/2012 Associate Professor (with Tenure), Institute of Neuroscience, National Yang Ming University, Taiwan
02/2004 - 01/2009 Assistant Professor, Institute of Neuroscience, National Yang-Ming University, Taiwan
02/2002 - 01/2004 Postdoctoral Fellow, Institute of Electrical Engineering, National Taiwan University, Taiwan
09/1995 - 06/1996 Network Engineer, Institute for Information Industry, Taiwan
09/1993 - 08/1995 Department Staff, National Health Research Institute, Taiwan
ADMINISTRATIVE EXPERIENCES
08/2022 - present Associate Dean of General Affairs, National Yang Ming Chiao Tung University, Taiwan
02/2022 - present Deputy Director, Medical Device Innovation and Translation R&D Center, National Yang Ming Chiao Tung University, Taiwan
02/2016 - 01/2022 Deputy Director, Aging and Health Research Center, National Yang Ming Chiao Tung University, Taiwan
10/2008 - present Director, MRI Core Facility, National Yang Ming Chiao Tung University, Taiwan
AWARDS AND HONOR
2021 Future Tech Award, Ministry of Science and Technology, Taiwan
2020 National Innovation Award, Taiwan
2020 Professor with permanently exempt from assessment, National Yang Ming Chiao Tung University
2019 PAC Model Award, Predictive Analytics Competition
2016 Award for executing Innovative Research Grant 3 times, National Health Research Institute
2016 12th The G. Nappi Cluster Headache Award
2011 12th The G. Nappi Cluster Headache Award
JOURNAL EDITORIAL ACTIVITIES
1. Associate Editor: Brain Connectivity
2. Associate Editor: Frontiers in Neuroscience, Section in Brain Imaging Methods
3. Editorial Board: Plos One
GRANT REVIEWING ACTIVITIES
1. Medical Research Council (MRC), UK (2017)
2. Agence Nationale De La Recherche (ANR), France (2013, 2014)
3. Ministry of Science and Technology, Taiwan (2000 – present)
ACADEMIC SOCIETY ACTIVITIES
1. Committee member, Asian Society of Magnetic Resonance in Medicine (2021 - present)
2. Committee member, Taiwan Magnetic Resonance Society (2020 - present)
3. Program committee: Organization for Human Brain Mapping (2010, 2011)
GRANTS DURING THE PAST FIVE YEARS
1. Development of micro brain surgery navigation system: Fusion of AI face recognition and brain image features for accurate positioning. MOST Emerging Technology Application Program (PI; 2022/1/1-2023/12/31; NTD 3,260,000)
2. Mapping the human brain connectome: Bridging microscale and macroscale organization. MOST Brain Project (PI; 2021/1/1-2022/12/31; NTD 18,000,000)
3. Mapping the human connectome: Bridging microscale and macroscale connectomics of the human brain. MOST Pre-Brain Project (PI; 2019/6/1-2020/12/31; NTD 9,500,000)
4. Cognitive Aging and Enhancement: Neural Basis of Scaffolding Theory of Aging and Cognition. MOST Brain and Cognitive Sciences Project (PI; 2018/1/1-2020/6/30; NTD 5,000,000)
5. Constructing Healthy Living in Super-Aged Society by Artificial Intelligence: From Geroprotective Intervention to Care Management. MOST (Co-PI; 2018/1/1-2021/12/31; NTD 60,000,000)
6. Brain network changes in first-episode schizophrenia progression: extension of imaging endophenotype. NHRI (PI; 2017/1/1-2019/12/31; NTD 7,500,000)
PATENTS
1. Patent Number: I 504382 (Taiwan) Title: A dental stimulator brain imaging Inventors: CP Lin, CP Jao Valid: 2015 - 2035
2. Patent Number: I614627 (Taiwan) Title: A method for neural tracts tracking (It has been technology transferred) Inventors: CP Lin, CY Lo, CT Chong Valid: 2018 - 2037
3. Patent Number: I679652 (Taiwan) Title: Method for individual brain morphometry assess Inventors: CP Lin, WC Lin, KH Chou Valid: 2019 - 2039
4. Patent Number: 10,497,120B2 (USA) Title: Method and apparatus of fiber tracing, and non-transitory computer-readable medium Inventors: CP Lin, CY Lo, CT Chong, CC Huang (It has been technology transferred) Valid: 2019 - 2040
5. Patent Number: I726574B (Taiwan) Title: Method for model training and electric device Inventors: CP Lin , LK Chen, KH Chou, CD Hsieh, CS Yu, SY Huang, MC Cheng Valid: 2020 - 2040
6. Patent Number: approved, waiting for license (Taiwan) Title: Method for White matter-based neurovascular age prediction Inventors: CP Lin, CC Huang Valid: 2022- 2042
INVITED TALKS DURING THE PAST SIX YEARS
1. Multimodal Integration- Combining DTI and fcMRI, 7th Biennial Conference on Resting State Brain Connectivity, Dallas, Texas, USA (Sep, 2019)
2. Mapping the connectomics of human brain disorders, ISMRM, Montreal, Canada (May, 2019)
3. Artificial intelligence in aging brain science, Shanghai innovation forum, Shanghai, China (Jul, 2018)
4. Mapping the structural connections in the living human brain, IEEE EMBS Neural Engineering Summer School, Shanghai, China (Aug. 2017)
5. Mapping the connectomics of human brain disorders, IEEE EMBS Neural Engineering Summer School, Shanghai, China (Aug. 2017)
6. Diffusion MRI Tractography for Neurosurgery, WFNS 16th World Congress of Neurosurgery, Istanbul, Turkey (Aug. 2017)
7. Reorganization of Brain Connectivity during Sleep, 1st Scientific and clinical meeting for sleep medicine, Suzhou, China (Nov. 2016)
8. Multimodal Integration- Combining DTI and fcMRI, 5th Biennial Conference on Resting State Brain Connectivity, Vienna, Austria (Sep. 2016)
PUBLICATIONS (僅列出今年度)
Total Number of Citations = 13863; H-Factor = 51
1. 1. Chu-Chung Huang, Kun-Hsien Chou, Wei-Ju Lee, Albert C. Yang, Shih-Jen Tsai, Liang-Kung Chen, Chih-Ping Chung*, Ching-Po Lin*. Brain white matter hyperintensities-predicted age reflects neurovascular health in middle-to-old aged subjects. Age & Ageing 2022 51(5):afac106
2. Yi-Chia Kung, Chia-Wei Li, Fan-Chi Hsiao, Pei-Jung Tsai, Shuo Chen, Ming-Kang Li, Hsin-Chien Lee, Chun-Yen Chang, Changwei W. Wu, Ching-Po Lin*. Cross-scale Dynamicity of Entropy and Connectivity in the Sleeping Brain. Brain Connectivity 2022 (in press)
3. Chih-Chin Heather Hsu, Shin Tai Chong, Yi-Chia Kung, Kuan-Tsen Kuo, Chu-Chung Huang, Ching-Po Lin*. Integrated Diffusion Image Operator (iDIO): A tool for automated configuration and processing of diffusion MRI data. bioRxiv 2022. https://doi.org/10.1101/2022.03.14.483870
4. Yi-Chia Wei, Yi-Chia Kung, Wen-Yi Huang, Chemin Lin, Yao-Liang Chen, Chih-Ken Chen, Yu-Chiau Shyu, Ching-Po Lin*. Functional Connectivity Dynamics Altered of the Resting Brain in Subjective Cognitive Decline. Frontiers in Aging Neuroscience, section Neurocognitive Aging and Behavior 2022 (In press)
5. Yi-Chia Wei, Wen-Yi Huang, Chih-Yu Jian, Chih-Chin Heather Hsu, Chih-Chung Hsu, Ching-Po Lin, Chi-Tung Cheng, Yao-Liang Chen, Hung-Yu Wei, Kuan-Fu Chen. Semantic segmentation guided detector for segmentation, classification, and lesion mapping of acute ischemic stroke in MRI images. NeuroImage: Clinical 2022; 103044
6. Chih-Ping Chung, Li-Ning Peng, Wei-Ju Lee, Pei-Ning Wang, Ching-Po Lin, Liang-Kung Chen. Cerebral small vessel disease is associated with concurrent physical and cognitive impairments at preclinical stage. Cerebral Circulation - Cognition and Behavior 2022; 3: 100144
7. Mingrui Xia, Jin Liu, Andrea Mechelli, Xiaoyi Sun, Qing Ma, Xiaoqin Wang, Dongtao Wei, Yuan Chen, Bangshan Liu, Chu-Chung Huang, Yanting Zheng, Yankun Wu, Taolin Chen, Yuqi Cheng, Xiufeng Xu, Qiyong Gong, Tian-Mei Si, Shijun Qiu, Ching-Po Lin, Jingliang Cheng, Yanqing Tang, Fei Wang, Jiang Qiu, Peng Xie, Lingjiang Li, Yong He. Connectome Gradient Dysfunction in Major Depression and Its Association with Gene Expression Profiles and Treatment Outcomes. Molecular Psychiatry 27(3): 1384-1393 (2022)
8. Chia-Shu Lin, Li-Kuo Liu, Wei-Ju Lee, Li-Ning Peng, Ching-Po Lin, Shyh-Yuan Lee, Liang-Kung Chen. Low masseter muscle mass is associated with frailty in community-dwelling older adults: I-Lan Longitudinal Aging Study. Experimental Gerontology 2022; 163:111777
9. Kai Niu, Xueyan Li, Li Zhang, Zhensong Yan, Wei Yu, Peipeng Liang, Yan Wang, Ching-Po Lin, Huimao Zhang, Chunjie Guo, Kuncheng Li, Tianyi Qian. Improving segmentation reliability of multi-scanner brain images using a generative adversarial network. Quant Imaging Med Surg. 2022; 12(3):1775-1786
10. Yi-Cheng Lin, Yun R Lien, Shang-Hua N. Lin, Yi-Chia Kung, Chu-Chung Huang, Ching-Po Lin, Li-Hung Chang Baseline cerebro-cerebellar functional connectivity in afferent and efferent pathways reveal dissociable improvements in visuomotor learning. Frontiers in Neuroscience 2022; 16: 904564
11. Yun Lien, Yi-Cheng Lin, Shang-Hua N. Lin, Ching-Po Lin, Li-Hung Chang. Frequency-dependent effects of cerebellar rTMS on visuomotor accuracy. Frontiers in Neuroscience 2022; 16: 804027
12. Chu-Chung Huang, Edmund T. Rolls, Jianfeng Feng, Ching-Po Lin. An extended Human Connectome Project multimodal parcellation atlas of the human cortex and subcortical areas. Brain Structure and Function 227(3): 763-778 (2022)
13. I-Ting Lee, Chu-Chung Huang, Po-Cheng Hsu, Ching-Po Lin, Po-Yi Tsai. Resting-State Network Changes Following Transcranial Magnetic Stimulation in Patients with Aphasia-A Randomized Controlled Study. Neuromodulation: Technology at the Neural Interface 2022 25(4):528-537
14. Po-Yuan Su, Yi-Chia Wei, Hao Luo, Chi-Hung Liu, Wen-Yi Huang, Kuan-Fu Chen, Ching-Po Lin, Hung-Yu Wei, Tsong-Hai Lee. Machine Learning Models for Predicting Influential Factors of Early Outcomes in Acute Ischemic Stroke: Registry-Based Study. JMIR Med Inform 2022;10(3):e32508
15. Cheng-Chia Lee, Sheng-Che Hung, Yi-Hsiu Chen, Hsin-Hung Chen, Chien Chen, Ching-Jen Chen, Hsiu-Mei Wu, Ching-Po Lin, Syu-Jyun Peng. Structural connectivity in children after total corpus callosotomy. Epilepsy Research 2022; 182: 106908
16. Tony Szu-Hsien Lee, Yi-Hsuan Liu, Yun-Ju Huang, Wai-Kwong Tang, Yifan Wang, Sien Hu, Ching-Po Lin, Chiang-Shan Ray Li, Chia-Chun Hung. Clinical and behavior characteristics of individuals who used ketamine. Scientific Reports 2022; 12(1):801
17. Hung Yu Liu, Kun-Hsien Chou, Pei-Lin Lee, Yen-Feng Wang, Shih-Pin Chen, Kuan-Lin Lai, Ching-Po Lin, Shuu-Jiun Wang, Wei-Ta Chen. The right anterior insula is associated with pain generalization in patients with fibromyalgia. Pain 2022; 163(4):e572-e579
18. Qiuyun Fan, Cornelius Eichner, Maryam Afzali, Lars Mueller, Chantal M.W. Tax, Mathias Davids, Mirsad Mahmutovic, Boris Keil, Berkin Bilgic, Kawin Setsompop, Hong-Hsi Lee, Qiyuan Tian, Chiara Maffei, Gabriel Ramos-Llordén, Aapo Nummenmaa, Thomas Witzel, Anastasia Yendiki, Yi-Qiao Song, Chu-Chung Huang, Ching-Po Lin, Nikolaus Weiskopf, Alfred Anwander, Derek K. Jones, Bruce R. Rosen, Lawrence L. Wald, Susie Y. Huang. Mapping the Human Connectome using Diffusion MRI at 300 mT/m Gradient Strength: Methodological Advances and Scientific Impact. Neuroimage 22;118958 (2022)
19. Wei Zhao, Valerie Voon, Kangkang Xue, Chao Xie, Jujiao Kang, Ching-Po Lin, Jijun Wang, Jingliang Cheng, Jianfeng Feng. Common abnormal connectivity in first-episode and chronic schizophrenia in pre- and post-central regions: Implications for neuromodulation targeting. Prog Neuropsychopharmacol Biol Psychiatry 117: 110556 (2022)
20. Chih-Ping Chung, Wei-Ju Lee, Kun-Hsien Chou, Pei-Lin Lee, Li-Ning Peng, Pei-Ning Wang, Ching-Po Lin, Liang-Kung Chen. Frailty and dementia risks in asymptomatic cerebral small vessel disease: A longitudinal cohort study. Archives of Gerontology and Geriatrics. 102: 104754 (2022)
21. Yi-Cheng Lin, Chih-Ping Chung, Pei-Lin Lee, Kun-Hsien Chou, Li-Hung Chang, Szu-Ying Lin, Yi-Jung Lee, Ching-Po Lin, Pei-Ning Wang. The Flexibility of Physio-Cognitive Decline Syndrome: A Longitudinal Cohort Study. Front Public Health. 10: 820383 (2022)
22. Yu Zhou, Xiaopeng Si, Yuanyuan Chen, Yiping Chao, Ching-Po Lin, Sicheng Li, Xingjian Zhang, Dong Ming , Qiang Li. Hippocampus- and Thalamus-Related Fiber-Specific White Matter Reductions in Mild Cognitive Impairment. Cerebral Cortex 2022; (in press)
23. Yajuan Zhang, Qiong Xiang, Chu-Chung Huang, Jiajia Zhao, Yuchen Liu, Ching-Po Lin, Dengtang Liu*, Chun Yi Zac Lo*. Short-term Medication Effects on Brain Functional Activity and Network Architecture in First-Episode Psychosis: A Longitudinal fMRI Study. Brain Imaging Behav. (in press