The Institute of Biomedical Engineering and Nanomedicine focuses on the areas of biomaterials and regenerative medicine, biomedical imaging, nano-medicine, and medical electronics; and it performs translational research in close collaboration with clinical institutions. The institute also forms close connections with local and international industrial players to enhance commercialization of its research products.
- Biomaterials and Regenerative Medicine
- Development of biodegradable and injectable bone cement for femur head angiogenesis and regeneration.
- Development of surface plasmon resonance technology for Chinese medicine and stimulative surface technology for tissue engineering, respectively.
- Development of a microfluidic hanging drop cell culture technique to miniaturize experiment setup and reduce cost.
- Biomedical Imaging
- A high-gradient-strength human MRI system, which provides high resolution and accuracy to map the brain connectomics.
- MR-guided focused ultrasound technology platform for non-invasive precision therapy.
- Explore states of nano-objects in liquid environment by K-kit (a Si-based micro channel device) on electron microscopy.
- Caged Pt nanocluster (NHRI-CPN) that can exert tumor-inside activation for anticancer chemotherapeutic with minimizing systemic toxicity is reported. The CPN has great potential to overcome cancers with cisplatin-like resistance, such as triple-negative breast cancer and lung cancer.
- Implantable radioactive gold nanoparticles can inhibit unresectable brain tumor cells after surgery and enhance the efficacy of follow-up concurrent chemoradiotherapy (CCRT) to avoid recurrence.
- Novel endogenous red blood cell-derived vesicles (RDV) as nanocarriers.
- Nanoparticle-enhanced tropism of stem cells to cancer and other diseases for therapy.
- A novel nanoplatform with X-ray activated photodynamic effect for molecular imaging-guided intensity modulated radiation nanotherapy to noninvasively treat deep-tissue cancers.
- Biomedical Electronics
- Monitoring neurovascular function recovery and blood-brain barrier integrity via multimodal in vivo imaging technology with peripheral sensory stimulation intervention in the rat photothrombosis model.
- Handheld Real-time Acoustic-Resolution Photoacoustic Imaging System with Fiber-bundle-based Illumination and Its In Vivo Application.
- Using electrocorticography-optical imaging technology to simultaneously monitor neurovascular dynamics with focused ultrasound neuromodulation intervention for epilepsy.