Abstract

Magnetic resonance imaging (MRI) observation of the living brain is depending on spatial resolution, signal-to-noise ratio (SNR), and tissue parameters such as relaxation time and contrast. The advent of 7 tesla (T) ultra-high-field MRI offers unprecedented capabilities for noninvasive imaging of human and animal brains. This technical capability covers a range of functional and structural domains and provides new opportunities for quantitative neurochemical measurements using MR spectroscopic techniques. In addition, increasing the static magnetic field promotes phase dispersion and shifts in the signal. As a result, the predicted benefits such as enhanced Blood Oxygenation Level Dependent (BOLD) effect, which is used to detect brain activity, and an improved signal-to-contrast-to-noise ratio (CNR). Using optimal measurement techniques, improved CNR allows the delineation of the brain microstructures, including the laminar structures of the cerebral cortex in vivo. In this talk, I would like to introduce our research of 7T in-vivo high-resolution human brain imaging. In addition, I would like to share our initial experience of the recently installed new 3T scanner equipped with high-performance gradient system (Gmax: 200 mT/m).