1993 - 1998Department of Bioengineering, University of California, San Diego, USAPh.D. in Bioengineering
1987 - 1991Department of Mechanical Engineering, National Taiwan University, TaiwanB.S. in Mechanical Engineering
2009.11 - presentDivision of Medical Engineering Research, National Health Research Institutes, TaiwanAssociate Investigator
2009.02 - presentDepartment of Biomedical Imaging and Radiological Sciences (BIRS), National Yang Ming University, Taipei, TaiwanAdjunct Assistant Professor
2003.08 - 2008.07Institute of Biomedical Engineering, National Yang Ming University, Taipei, TaiwanAdjunct Assistant Professor
2001.11 - 2009.11Division of Medical Engineering Research, National Health Research Institutes, TaiwanAssistant Investigator
1998.09 - 2001.10Division of Endocrinology and Metabolism, Lab of Professor Wolfgang Dillmann, MD, Department of Medicine, University of California, San Diego, La Jolla, CA, USAPostdoctoral Research Fellow
1. Inducible transgenic models and developing multimodal molecular imaging tools to be applied in a variety of disciplines, including cancer and inflammatory diseases
2. Regulatory roles of the stretching force in cell/tissue/organ development
Research Activities & Accomplishment
Lin K, Hollander JM, Kao V, Lian I, Lin B, Dillmann WH. Myocyte protection of rat neonatal cardiac myocytes death by 10 kD heat shock protein (Hsp10) involves the mobile loop and attenuation of Ras GTP-ase pathway. FASEB J. 10.1096/fj.03-0348fje, 2004.
Hollander JM, Lin K, Scott B, Dillmann WH. Overexpression of PHGPx and HSP60/10 Protects against Ischemia/Reoxygenation Injury. Free Radical Biology & Medicine 35(7):742-751, 2003.
Das DK, Dillmann W, Ho YS, Lin KM, Gloss BR. Using genetically engineered mice to study myocardial ischemia-reperfusion injury. Methods Enzymol 353:346-65, 2002.
Lin K, Lin B, Lian I, Mestril R, Scheffler I, Dillmann WH. Combined and individual mitochondrial HSP60 and HSP10 expression in cardiac myocytes protects mitochondrial function and prevents apoptotic cell deaths induced by simulated ischemia-reoxygenation. Circulation 103:1787-1792, 2001.
Lin K, Hsu PP, Chen BP, Yuan S, Usami S, Shyy JY, Li YS, Chien S Molecular mechanism of endothelial growth arrest by laminar shear stress. Proc Natl Acad Sci U S A. 97(17):9385-9, 2000.
Lin M, Almus-Jacobs F, Chen H, Parry GC, Mackman N, Shyy JY, Chien S. Shear stress induction of the tissue factor gene. J. Clin. Invest. 99(4):737-44, 1997.
Shyy JY, Lin MC, Han J, Lu Y, Petrime M, Chien S The cis-acting phorbol ester "12-O-tetradecanoylphorbol 13-acetate"-responsive element is involved in shear stress-induced monocyte chemotactic protein 1 gene expression. Proc Natl Acad Sci U S A. 92(17):8069-73, 1995.